George M. and his sister Josie, when they were, with their parents, part of The Four Cohans, a family vaudeville act, before George became the King Of Broadway.
Josie later married the silent film director Fred Niblo. Josie died of heart disease at a relatively young age, in 1916, the year Niblo entered movies as an actor and director. He's best known for directing the silent version of Ben-Hur, but a film he made a year later with Garbo, The Temptress, is probably his best work.